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IL-15 signaling promotes adoptive effector T-cell survival and memory formation in irradiation-induced lymphopenia

BACKGROUND: Lymphopenia promotes naïve T-cell homeostatic proliferation and adoptive effector T-cell survival and memory formation. IL-7 plays a critical role in homeostatic proliferation, survival and memory formation of naïve T-cells in lymphopenia, and its underlying molecular mechanism has also...

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Detalles Bibliográficos
Autores principales:	Xu, Aizhang, Bhanumathy, Kalpana Kalyanasundaram, Wu, Jie, Ye, Zhenmin, Freywald, Andrew, Leary, Scot C., Li, Rongxiu, Xiang, Jim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858849/ https://www.ncbi.nlm.nih.gov/pubmed/27158441 http://dx.doi.org/10.1186/s13578-016-0098-2

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