RISC-mediated control of selected chromatin regulators stabilizes ground state pluripotency of mouse embryonic stem cells

BACKGROUND: Embryonic stem cells are intrinsically unstable and differentiate spontaneously if they are not shielded from external stimuli. Although the nature of such instability is still controversial, growing evidence suggests that protein translation control may play a crucial role. RESULTS: We...

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Detalles Bibliográficos
Autores principales: Pandolfini, Luca, Luzi, Ettore, Bressan, Dario, Ucciferri, Nadia, Bertacchi, Michele, Brandi, Rossella, Rocchiccioli, Silvia, D’Onofrio, Mara, Cremisi, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858858/
https://www.ncbi.nlm.nih.gov/pubmed/27154007
http://dx.doi.org/10.1186/s13059-016-0952-x

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