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Interleukin-25 is detrimental for recovery after spinal cord injury in mice

BACKGROUND: The cytokine, interleukin (IL)-25, is thought to be critically involved in inducing a type 2 immune response which may contribute to regeneration after central nervous system (CNS) trauma. We investigated whether applying recombinant IL-25, locally or systemically, in a mouse model of sp...

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Detalles Bibliográficos
Autores principales: Dooley, Dearbhaile, Lemmens, Evi, Ponsaerts, Peter, Hendrix, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858907/
https://www.ncbi.nlm.nih.gov/pubmed/27154002
http://dx.doi.org/10.1186/s12974-016-0566-y