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The octanol/water distribution coefficients of ardipusilloside-I and its metabolites, and their permeation characteristics across Caco-2 cell monolayer

BACKGROUND: Ardipusilloside-I (ADS-I) is a triterpenoid saponin extracted from Chinese medicinal herb Ardisiapusill A. DC. Previous studies have demonstrated the potent anti-tumor activities of ADS-I both in vitro and in vivo, and its main metabolites (M1 and M2) from human intestinal bacteria. Howe...

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Detalles Bibliográficos
Autores principales:	Cao, Wei-yu, Feng, Bin, Cheng, Li-fei, Wang, Ying, Wang, Ji, Wang, Xiao-juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858920/ https://www.ncbi.nlm.nih.gov/pubmed/27158260 http://dx.doi.org/10.1186/s13065-016-0175-y

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