Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice

BACKGROUND: Peptidylarginine deiminase type 4 (PADI4) has been identified as a susceptibility gene for rheumatoid arthritis (RA) by genome-wide association studies. PADI4 is highly expressed in the bone marrow, macrophages, neutrophils, and monocytes. Peptidyl citrulline is an interesting molecule i...

Descripción completa

Detalles Bibliográficos
Autores principales: Suzuki, Akari, Kochi, Yuta, Shoda, Hirofumi, Seri, Yu, Fujio, Keishi, Sawada, Tetsuji, Yamada, Ryo, Yamamoto, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858923/
https://www.ncbi.nlm.nih.gov/pubmed/27150598
http://dx.doi.org/10.1186/s12891-016-1055-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858923/
https://www.ncbi.nlm.nih.gov/pubmed/27150598
http://dx.doi.org/10.1186/s12891-016-1055-2

Ejemplares similares