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Decreased severity of experimental autoimmune arthritis in peptidylarginine deiminase type 4 knockout mice

BACKGROUND: Peptidylarginine deiminase type 4 (PADI4) has been identified as a susceptibility gene for rheumatoid arthritis (RA) by genome-wide association studies. PADI4 is highly expressed in the bone marrow, macrophages, neutrophils, and monocytes. Peptidyl citrulline is an interesting molecule i...

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Detalles Bibliográficos
Autores principales:	Suzuki, Akari, Kochi, Yuta, Shoda, Hirofumi, Seri, Yu, Fujio, Keishi, Sawada, Tetsuji, Yamada, Ryo, Yamamoto, Kazuhiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858923/ https://www.ncbi.nlm.nih.gov/pubmed/27150598 http://dx.doi.org/10.1186/s12891-016-1055-2

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