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Transient Receptor Potential Vanilloid 4 Ion Channel Functions as a Pruriceptor in Epidermal Keratinocytes to Evoke Histaminergic Itch

TRPV4 ion channels function in epidermal keratinocytes and in innervating sensory neurons; however, the contribution of the channel in either cell to neurosensory function remains to be elucidated. We recently reported TRPV4 as a critical component of the keratinocyte machinery that responds to ultr...

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Detalles Bibliográficos
Autores principales: Chen, Yong, Fang, Quan, Wang, Zilong, Zhang, Jennifer Y., MacLeod, Amanda S., Hall, Russell P., Liedtke, Wolfgang B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4858974/
https://www.ncbi.nlm.nih.gov/pubmed/26961876
http://dx.doi.org/10.1074/jbc.M116.716464