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Effect of current glycemic control on qualitative body composition in sedentary ambulatory Type 2 diabetics

BACKGROUND: Obesity and Type 2 diabetes mellitus are on rise with cause–effect relationship. Diabetics monitor blood sugar, neglecting qualitative body composition, leaving residual threat of ectopic fat unattended. We tried to correlate glycemic triad with parameters of body composition derived obj...

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Autores principales: Solanki, Jayesh Dalpatbhai, Makwana, Amit H., Mehta, Hemant B., Kamdar, Panna, Gokhale, Pradnya A., Shah, Chinmay J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859114/
https://www.ncbi.nlm.nih.gov/pubmed/27185972
http://dx.doi.org/10.4103/0300-1652.180562
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author Solanki, Jayesh Dalpatbhai
Makwana, Amit H.
Mehta, Hemant B.
Kamdar, Panna
Gokhale, Pradnya A.
Shah, Chinmay J.
author_facet Solanki, Jayesh Dalpatbhai
Makwana, Amit H.
Mehta, Hemant B.
Kamdar, Panna
Gokhale, Pradnya A.
Shah, Chinmay J.
author_sort Solanki, Jayesh Dalpatbhai
collection PubMed
description BACKGROUND: Obesity and Type 2 diabetes mellitus are on rise with cause–effect relationship. Diabetics monitor blood sugar, neglecting qualitative body composition, leaving residual threat of ectopic fat unattended. We tried to correlate glycemic triad with parameters of body composition derived objectively by bioelectrical impedance analysis (BIA). MATERIALS AND METHODS: A sample of 78 under treatment sedentary Type 2 diabetics of either sex with known glycemic and lipidemic control from our city. Following baseline assessment measurement was done by instrument Omron Karada Scan (Model HBF-510, China) using the principle of tetra poplar BIA to derive parameters of body composition. We tried to correlate glycemic triad with these parameters, both directly as well as after defining them as per established cutoff norms. RESULTS: We found poor glycemic control in the study group (20% for Hb1AC), high body mass index, subcutaneous fat, visceral fat (VF), total body fat (TBF), and lesser mass of skeletal muscle in Type 2 diabetics. However, there were small, insignificant, and inconsistent difference of these parameters while directly correlating with the fasting blood sugar, postprandial blood sugar, and glycosylated hemoglobin. On qualitative assessment, the impact of glycemic control as per standard norms, the risk of high VF, high TBF, low skeletal muscle mass was though high (between 1 and 2) in Type 2 diabetics with poor glycemic control as compared to good glycemics, but each strength lacks statistical significance. CONCLUSION: BIA reveals that Type 2 diabetics have more ectopic fat on expense of skeletal muscle that do not correlate with current glycemic status, both quantitatively and qualitatively. Measurement of body composition can be included and subjects can be motivated for lifestyle modification strategies while managing metabolic derangements of Type 2 diabetes.
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spelling pubmed-48591142016-05-16 Effect of current glycemic control on qualitative body composition in sedentary ambulatory Type 2 diabetics Solanki, Jayesh Dalpatbhai Makwana, Amit H. Mehta, Hemant B. Kamdar, Panna Gokhale, Pradnya A. Shah, Chinmay J. Niger Med J Original Article BACKGROUND: Obesity and Type 2 diabetes mellitus are on rise with cause–effect relationship. Diabetics monitor blood sugar, neglecting qualitative body composition, leaving residual threat of ectopic fat unattended. We tried to correlate glycemic triad with parameters of body composition derived objectively by bioelectrical impedance analysis (BIA). MATERIALS AND METHODS: A sample of 78 under treatment sedentary Type 2 diabetics of either sex with known glycemic and lipidemic control from our city. Following baseline assessment measurement was done by instrument Omron Karada Scan (Model HBF-510, China) using the principle of tetra poplar BIA to derive parameters of body composition. We tried to correlate glycemic triad with these parameters, both directly as well as after defining them as per established cutoff norms. RESULTS: We found poor glycemic control in the study group (20% for Hb1AC), high body mass index, subcutaneous fat, visceral fat (VF), total body fat (TBF), and lesser mass of skeletal muscle in Type 2 diabetics. However, there were small, insignificant, and inconsistent difference of these parameters while directly correlating with the fasting blood sugar, postprandial blood sugar, and glycosylated hemoglobin. On qualitative assessment, the impact of glycemic control as per standard norms, the risk of high VF, high TBF, low skeletal muscle mass was though high (between 1 and 2) in Type 2 diabetics with poor glycemic control as compared to good glycemics, but each strength lacks statistical significance. CONCLUSION: BIA reveals that Type 2 diabetics have more ectopic fat on expense of skeletal muscle that do not correlate with current glycemic status, both quantitatively and qualitatively. Measurement of body composition can be included and subjects can be motivated for lifestyle modification strategies while managing metabolic derangements of Type 2 diabetes. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4859114/ /pubmed/27185972 http://dx.doi.org/10.4103/0300-1652.180562 Text en Copyright: © Nigerian Medical Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution NonCommercial ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Solanki, Jayesh Dalpatbhai
Makwana, Amit H.
Mehta, Hemant B.
Kamdar, Panna
Gokhale, Pradnya A.
Shah, Chinmay J.
Effect of current glycemic control on qualitative body composition in sedentary ambulatory Type 2 diabetics
title Effect of current glycemic control on qualitative body composition in sedentary ambulatory Type 2 diabetics
title_full Effect of current glycemic control on qualitative body composition in sedentary ambulatory Type 2 diabetics
title_fullStr Effect of current glycemic control on qualitative body composition in sedentary ambulatory Type 2 diabetics
title_full_unstemmed Effect of current glycemic control on qualitative body composition in sedentary ambulatory Type 2 diabetics
title_short Effect of current glycemic control on qualitative body composition in sedentary ambulatory Type 2 diabetics
title_sort effect of current glycemic control on qualitative body composition in sedentary ambulatory type 2 diabetics
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859114/
https://www.ncbi.nlm.nih.gov/pubmed/27185972
http://dx.doi.org/10.4103/0300-1652.180562
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