Complete Genome Sequence of Streptomyces venezuelae ATCC 15439, Producer of the Methymycin/Pikromycin Family of Macrolide Antibiotics, Using PacBio Technology

Here, we report the complete genome sequence of Streptomyces venezuelae ATCC 15439, a producer of the methymycin/pikromycin family of macrolide antibiotics and a model host for natural product studies, obtained exclusively using PacBio sequencing technology. The 9.03-Mbp genome harbors 8,775 genes a...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Jingxuan, Sundararajan, Anitha, Devitt, Nicholas P., Schilkey, Faye D., Ramaraj, Thiruvarangan, Melançon, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859184/
https://www.ncbi.nlm.nih.gov/pubmed/27151802
http://dx.doi.org/10.1128/genomeA.00337-16
_version_ 1782430927856599040
author He, Jingxuan
Sundararajan, Anitha
Devitt, Nicholas P.
Schilkey, Faye D.
Ramaraj, Thiruvarangan
Melançon, Charles E.
author_facet He, Jingxuan
Sundararajan, Anitha
Devitt, Nicholas P.
Schilkey, Faye D.
Ramaraj, Thiruvarangan
Melançon, Charles E.
author_sort He, Jingxuan
collection PubMed
description Here, we report the complete genome sequence of Streptomyces venezuelae ATCC 15439, a producer of the methymycin/pikromycin family of macrolide antibiotics and a model host for natural product studies, obtained exclusively using PacBio sequencing technology. The 9.03-Mbp genome harbors 8,775 genes and 11 polyketide and nonribosomal peptide natural product gene clusters.
format Online
Article
Text
id pubmed-4859184
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher American Society for Microbiology
record_format MEDLINE/PubMed
spelling pubmed-48591842016-05-06 Complete Genome Sequence of Streptomyces venezuelae ATCC 15439, Producer of the Methymycin/Pikromycin Family of Macrolide Antibiotics, Using PacBio Technology He, Jingxuan Sundararajan, Anitha Devitt, Nicholas P. Schilkey, Faye D. Ramaraj, Thiruvarangan Melançon, Charles E. Genome Announc Prokaryotes Here, we report the complete genome sequence of Streptomyces venezuelae ATCC 15439, a producer of the methymycin/pikromycin family of macrolide antibiotics and a model host for natural product studies, obtained exclusively using PacBio sequencing technology. The 9.03-Mbp genome harbors 8,775 genes and 11 polyketide and nonribosomal peptide natural product gene clusters. American Society for Microbiology 2016-05-05 /pmc/articles/PMC4859184/ /pubmed/27151802 http://dx.doi.org/10.1128/genomeA.00337-16 Text en Copyright © 2016 He et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/) .
spellingShingle Prokaryotes
He, Jingxuan
Sundararajan, Anitha
Devitt, Nicholas P.
Schilkey, Faye D.
Ramaraj, Thiruvarangan
Melançon, Charles E.
Complete Genome Sequence of Streptomyces venezuelae ATCC 15439, Producer of the Methymycin/Pikromycin Family of Macrolide Antibiotics, Using PacBio Technology
title Complete Genome Sequence of Streptomyces venezuelae ATCC 15439, Producer of the Methymycin/Pikromycin Family of Macrolide Antibiotics, Using PacBio Technology
title_full Complete Genome Sequence of Streptomyces venezuelae ATCC 15439, Producer of the Methymycin/Pikromycin Family of Macrolide Antibiotics, Using PacBio Technology
title_fullStr Complete Genome Sequence of Streptomyces venezuelae ATCC 15439, Producer of the Methymycin/Pikromycin Family of Macrolide Antibiotics, Using PacBio Technology
title_full_unstemmed Complete Genome Sequence of Streptomyces venezuelae ATCC 15439, Producer of the Methymycin/Pikromycin Family of Macrolide Antibiotics, Using PacBio Technology
title_short Complete Genome Sequence of Streptomyces venezuelae ATCC 15439, Producer of the Methymycin/Pikromycin Family of Macrolide Antibiotics, Using PacBio Technology
title_sort complete genome sequence of streptomyces venezuelae atcc 15439, producer of the methymycin/pikromycin family of macrolide antibiotics, using pacbio technology
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859184/
https://www.ncbi.nlm.nih.gov/pubmed/27151802
http://dx.doi.org/10.1128/genomeA.00337-16
work_keys_str_mv AT hejingxuan completegenomesequenceofstreptomycesvenezuelaeatcc15439producerofthemethymycinpikromycinfamilyofmacrolideantibioticsusingpacbiotechnology
AT sundararajananitha completegenomesequenceofstreptomycesvenezuelaeatcc15439producerofthemethymycinpikromycinfamilyofmacrolideantibioticsusingpacbiotechnology
AT devittnicholasp completegenomesequenceofstreptomycesvenezuelaeatcc15439producerofthemethymycinpikromycinfamilyofmacrolideantibioticsusingpacbiotechnology
AT schilkeyfayed completegenomesequenceofstreptomycesvenezuelaeatcc15439producerofthemethymycinpikromycinfamilyofmacrolideantibioticsusingpacbiotechnology
AT ramarajthiruvarangan completegenomesequenceofstreptomycesvenezuelaeatcc15439producerofthemethymycinpikromycinfamilyofmacrolideantibioticsusingpacbiotechnology
AT melanconcharlese completegenomesequenceofstreptomycesvenezuelaeatcc15439producerofthemethymycinpikromycinfamilyofmacrolideantibioticsusingpacbiotechnology

Ejemplares similares