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Orthognathic Consequences of Sphincter Pharyngoplasty in Cleft Patients: A 2-Institutional Study

BACKGROUND: Understanding long-term sequelae of cleft treatment is paramount in the refinement of treatment algorithms to accomplish optimized immediate and long-term outcomes. In this study, we reviewed sphincter pharyngoplasties as a method of velopharyngeal insufficiency (VPI) treatment in relati...

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Autores principales: Yoshikane, Frances, Lai, Li Han, Hui, Brian K., Martins, Deborah B., Farias-Eisner, Gina, Mandelbaum, Rachel S., Hoang, Han, Bradley, James P., Wilson, Libby, Lee, Justine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859235/
https://www.ncbi.nlm.nih.gov/pubmed/27200238
http://dx.doi.org/10.1097/GOX.0000000000000656
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author Yoshikane, Frances
Lai, Li Han
Hui, Brian K.
Martins, Deborah B.
Farias-Eisner, Gina
Mandelbaum, Rachel S.
Hoang, Han
Bradley, James P.
Wilson, Libby
Lee, Justine C.
author_facet Yoshikane, Frances
Lai, Li Han
Hui, Brian K.
Martins, Deborah B.
Farias-Eisner, Gina
Mandelbaum, Rachel S.
Hoang, Han
Bradley, James P.
Wilson, Libby
Lee, Justine C.
author_sort Yoshikane, Frances
collection PubMed
description BACKGROUND: Understanding long-term sequelae of cleft treatment is paramount in the refinement of treatment algorithms to accomplish optimized immediate and long-term outcomes. In this study, we reviewed sphincter pharyngoplasties as a method of velopharyngeal insufficiency (VPI) treatment in relationship to orthognathic surgery. METHODS: Cleft lip/palate and cleft palate patients, 15 years of age and older, were reviewed for demographics, VPI surgery, revisions, and subsequent orthognathic surgery at 2 institutions. Chi-square test, Student’s t test, and logistic regression analyses were performed. RESULTS: In 214 patients reviewed (mean age, 19.5 years), 61.7% were male, 18.2% had isolated cleft palate, 61.2% had unilateral cleft lip and palate, and 20.6% had bilateral cleft lip and palate. A total of 33.6% were diagnosed with VPI and received a sphincter pharyngoplasty (mean age, 11.9 years). When subsequent orthognathic surgery was examined, sphincter pharyngoplasty was not associated with maxillary advancement (P = 0.59) but did correlate with an increase in mandibular surgery from 2.8% to 11.1% (P = 0.02). The indications for mandibular surgery in the pharyngoplasty population were related to congenital micrognathia. When cephalometric analyses were evaluated, sphincter pharyngoplasty resulted in a decreased sella-to-nasion-to-B point angle (mean, 79.0–76.3 degrees, P = 0.02) and a higher incidence of normal to class II maxillomandibular relationships as defined by A point-to-nasion-to-B point angles >0.5 (P = 0.02). CONCLUSIONS: Sphincter pharyngoplasty decreases anterior mandibular growth and the discrepancy between maxillomandibular skeletal relationships because of the frequent predisposition of cleft patients to maxillary hypoplasia. In patients with congenital mandibular micrognathia, a small increase in mandibular surgeries may occur.
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spelling pubmed-48592352016-05-19 Orthognathic Consequences of Sphincter Pharyngoplasty in Cleft Patients: A 2-Institutional Study Yoshikane, Frances Lai, Li Han Hui, Brian K. Martins, Deborah B. Farias-Eisner, Gina Mandelbaum, Rachel S. Hoang, Han Bradley, James P. Wilson, Libby Lee, Justine C. Plast Reconstr Surg Glob Open Original Article BACKGROUND: Understanding long-term sequelae of cleft treatment is paramount in the refinement of treatment algorithms to accomplish optimized immediate and long-term outcomes. In this study, we reviewed sphincter pharyngoplasties as a method of velopharyngeal insufficiency (VPI) treatment in relationship to orthognathic surgery. METHODS: Cleft lip/palate and cleft palate patients, 15 years of age and older, were reviewed for demographics, VPI surgery, revisions, and subsequent orthognathic surgery at 2 institutions. Chi-square test, Student’s t test, and logistic regression analyses were performed. RESULTS: In 214 patients reviewed (mean age, 19.5 years), 61.7% were male, 18.2% had isolated cleft palate, 61.2% had unilateral cleft lip and palate, and 20.6% had bilateral cleft lip and palate. A total of 33.6% were diagnosed with VPI and received a sphincter pharyngoplasty (mean age, 11.9 years). When subsequent orthognathic surgery was examined, sphincter pharyngoplasty was not associated with maxillary advancement (P = 0.59) but did correlate with an increase in mandibular surgery from 2.8% to 11.1% (P = 0.02). The indications for mandibular surgery in the pharyngoplasty population were related to congenital micrognathia. When cephalometric analyses were evaluated, sphincter pharyngoplasty resulted in a decreased sella-to-nasion-to-B point angle (mean, 79.0–76.3 degrees, P = 0.02) and a higher incidence of normal to class II maxillomandibular relationships as defined by A point-to-nasion-to-B point angles >0.5 (P = 0.02). CONCLUSIONS: Sphincter pharyngoplasty decreases anterior mandibular growth and the discrepancy between maxillomandibular skeletal relationships because of the frequent predisposition of cleft patients to maxillary hypoplasia. In patients with congenital mandibular micrognathia, a small increase in mandibular surgeries may occur. Wolters Kluwer Health 2016-04-07 /pmc/articles/PMC4859235/ /pubmed/27200238 http://dx.doi.org/10.1097/GOX.0000000000000656 Text en Copyright © 2016 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. All rights reserved. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.
spellingShingle Original Article
Yoshikane, Frances
Lai, Li Han
Hui, Brian K.
Martins, Deborah B.
Farias-Eisner, Gina
Mandelbaum, Rachel S.
Hoang, Han
Bradley, James P.
Wilson, Libby
Lee, Justine C.
Orthognathic Consequences of Sphincter Pharyngoplasty in Cleft Patients: A 2-Institutional Study
title Orthognathic Consequences of Sphincter Pharyngoplasty in Cleft Patients: A 2-Institutional Study
title_full Orthognathic Consequences of Sphincter Pharyngoplasty in Cleft Patients: A 2-Institutional Study
title_fullStr Orthognathic Consequences of Sphincter Pharyngoplasty in Cleft Patients: A 2-Institutional Study
title_full_unstemmed Orthognathic Consequences of Sphincter Pharyngoplasty in Cleft Patients: A 2-Institutional Study
title_short Orthognathic Consequences of Sphincter Pharyngoplasty in Cleft Patients: A 2-Institutional Study
title_sort orthognathic consequences of sphincter pharyngoplasty in cleft patients: a 2-institutional study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859235/
https://www.ncbi.nlm.nih.gov/pubmed/27200238
http://dx.doi.org/10.1097/GOX.0000000000000656
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