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Two‐Pore K(+) Channel TREK‐1 Regulates Sinoatrial Node Membrane Excitability

BACKGROUND: Two‐pore K(+) channels have emerged as potential targets to selectively regulate cardiac cell membrane excitability; however, lack of specific inhibitors and relevant animal models has impeded the effort to understand the role of 2‐pore K(+) channels in the heart and their potential as a...

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Detalles Bibliográficos
Autores principales: Unudurthi, Sathya D., Wu, Xiangqiong, Qian, Lan, Amari, Foued, Onal, Birce, Li, Ning, Makara, Michael A., Smith, Sakima A., Snyder, Jedidiah, Fedorov, Vadim V., Coppola, Vincenzo, Anderson, Mark E., Mohler, Peter J., Hund, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859279/
https://www.ncbi.nlm.nih.gov/pubmed/27098968
http://dx.doi.org/10.1161/JAHA.115.002865