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Full Expression of Cardiomyopathy Is Partly Dependent on B‐Cells: A Pathway That Involves Cytokine Activation, Immunoglobulin Deposition, and Activation of Apoptosis

BACKGROUND: Limited information exists on the role of B‐cell‐dependent mechanisms in the progression of heart failure (HF). However, in failing human myocardium, there is evidence of deposition of activated complement components as well as anticardiac antibodies. We aimed to determine the contributi...

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Detalles Bibliográficos
Autores principales: Cordero‐Reyes, Andrea M., Youker, Keith A., Trevino, Alejandro R., Celis, Rene, Hamilton, Dale J., Flores‐Arredondo, Jose H., Orrego, Carlos M., Bhimaraj, Arvind, Estep, Jerry D., Torre‐Amione, Guillermo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859365/
https://www.ncbi.nlm.nih.gov/pubmed/26769625
http://dx.doi.org/10.1161/JAHA.115.002484