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Rac1 Signaling Is Required for Anterior Second Heart Field Cellular Organization and Cardiac Outflow Tract Development
BACKGROUND: The small GTPase Rac1 regulates diverse cellular functions, including both apicobasal and planar cell polarity pathways; however, its role in cardiac outflow tract (OFT) development remains unknown. In the present study, we aimed to examine the role of Rac1 in the anterior second heart f...
Autores principales: | Leung, Carmen, Liu, Yin, Lu, Xiangru, Kim, Mella, Drysdale, Thomas A., Feng, Qingping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859369/ https://www.ncbi.nlm.nih.gov/pubmed/26722124 http://dx.doi.org/10.1161/JAHA.115.002508 |
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