Preserved Autonomic Cardiovascular Regulation With Cardiac Pacemaker Inhibition: A Crossover Trial Using High‐Fidelity Cardiovascular Phenotyping

BACKGROUND: Sympathetic and parasympathetic influences on heart rate (HR), which are governed by baroreflex mechanisms, are integrated at the cardiac sinus node through hyperpolarization‐activated cyclic nucleotide–gated channels (HCN4). We hypothesized that HCN4 blockade with ivabradine selectively...

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Detalles Bibliográficos
Autores principales: Heusser, Karsten, Tank, Jens, Brinkmann, Julia, Schroeder, Christoph, May, Marcus, Großhennig, Anika, Wenzel, Daniela, Diedrich, André, Sweep, Fred C. G. J., Mehling, Heidrun, Luft, Friedrich C., Jordan, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859385/
https://www.ncbi.nlm.nih.gov/pubmed/26764413
http://dx.doi.org/10.1161/JAHA.115.002674

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