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A Comprehensive In Silico Analysis on the Structural and Functional Impact of SNPs in the Congenital Heart Defects Associated with NKX2-5 Gene—A Molecular Dynamic Simulation Approach

Congenital heart defects (CHD) presented as structural defects in the heart and blood vessels during birth contribute an important cause of childhood morbidity and mortality worldwide. Many Single nucletotide polymorphisms (SNPs) in different genes have been associated with various types of congenit...

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Detalles Bibliográficos
Autores principales: Abdul Samad, Firoz, Suliman, Bandar A., Basha, Syed Hussain, Manivasagam, Thamilarasan, Essa, Musthafa Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859487/
https://www.ncbi.nlm.nih.gov/pubmed/27152669
http://dx.doi.org/10.1371/journal.pone.0153999

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