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Inhibition of Cell Proliferation in an NRAS Mutant Melanoma Cell Line by Combining Sorafenib and α-Mangostin

α-Mangostin is a natural product commonly used in Asia for cosmetic and medicinal applications including topical treatment of acne and skin cancer. Towards finding new pharmacological strategies that overcome NRAS mutant melanoma, we performed a cell proliferation-based combination screen using a co...

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Detalles Bibliográficos
Autores principales: Xia, Yun, Li, Ying, Westover, Kenneth D., Sun, Jiaming, Chen, Hongxiang, Zhang, Jianming, Fisher, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859503/
https://www.ncbi.nlm.nih.gov/pubmed/27152946
http://dx.doi.org/10.1371/journal.pone.0155217