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Investigations of the CLOCK and BMAL1 Proteins Binding to DNA: A Molecular Dynamics Simulation Study
The circadian locomotor output cycles kaput (CLOCK), and brain and muscle ARNT-like 1 (BMAL1) proteins are important transcriptional factors of the endogenous circadian clock. The CLOCK and BMAL1 proteins can regulate the transcription-translation activities of the clock-related genes through the DN...
Autores principales: | Xue, Tuo, Song, Chunnian, Wang, Qing, Wang, Yan, Chen, Guangju |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859532/ https://www.ncbi.nlm.nih.gov/pubmed/27153104 http://dx.doi.org/10.1371/journal.pone.0155105 |
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