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Enhancement of Transcription by a Splicing-Competent Intron Is Dependent on Promoter Directionality
Enhancement of transcription by a splicing-competent intron is an evolutionarily conserved feature among eukaryotes. The molecular mechanism underlying the phenomenon, however, is not entirely clear. Here we show that the intron is an important regulator of promoter directionality. Employing strand-...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859611/ https://www.ncbi.nlm.nih.gov/pubmed/27152651 http://dx.doi.org/10.1371/journal.pgen.1006047 |