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Quantitative perturbation-based analysis of gene expression predicts enhancer activity in early Drosophila embryo

Enhancers constitute one of the major components of regulatory machinery of metazoans. Although several genome-wide studies have focused on finding and locating enhancers in the genomes, the fundamental principles governing their internal architecture and cis-regulatory grammar remain elusive. Here,...

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Detalles Bibliográficos
Autores principales: Sayal, Rupinder, Dresch, Jacqueline M, Pushel, Irina, Taylor, Benjamin R, Arnosti, David N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859806/
https://www.ncbi.nlm.nih.gov/pubmed/27152947
http://dx.doi.org/10.7554/eLife.08445