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Fibronectin EDA and CpG synergize to enhance antigen-specific Th1 and cytotoxic responses
Subunit vaccines, employing purified protein antigens rather than intact pathogens, require the addition of adjuvants for enhanced immunogenicity with a correct balance between strong activation of the immune system and low toxicity. Here we show that the endogenous (i.e., autologous) non-toxic TLR4...
Autores principales: | Julier, Ziad, de Titta, Alexandre, Grimm, Alizée J., Simeoni, Eleonora, Swartz, Melody A., Hubbell, Jeffrey A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859824/ https://www.ncbi.nlm.nih.gov/pubmed/27016652 http://dx.doi.org/10.1016/j.vaccine.2016.03.057 |
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