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Ajulemic acid exerts potent anti-fibrotic effect during the fibrogenic phase of bleomycin lung
BACKGROUND: Ajulemic acid (AjA) is a synthetic analogue of tetrahydrocannabinol that can prevent and limit progression of skin fibrosis in experimental systemic sclerosis. In this study we investigated whether AjA also prevents and modulates lung fibrosis induced by bleomycin (BLM) when administered...
Autores principales: | Lucattelli, Monica, Fineschi, Silvia, Selvi, Enrico, Garcia Gonzalez, Estrella, Bartalesi, Barbara, De Cunto, Giovanna, Lorenzini, Sauro, Galeazzi, Mauro, Lungarella, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859981/ https://www.ncbi.nlm.nih.gov/pubmed/27153807 http://dx.doi.org/10.1186/s12931-016-0373-0 |
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