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Obesity-related DNA methylation at imprinted genes in human sperm: Results from the TIEGER study

BACKGROUND: Epigenetic reprogramming in mammalian gametes resets methylation marks that regulate monoallelic expression of imprinted genes. In males, this involves erasure of the maternal methylation marks and establishment of paternal-specific methylation to appropriately guide normal development....

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Detalles Bibliográficos
Autores principales: Soubry, Adelheid, Guo, Lisa, Huang, Zhiqing, Hoyo, Cathrine, Romanus, Stephanie, Price, Thomas, Murphy, Susan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859994/
https://www.ncbi.nlm.nih.gov/pubmed/27158277
http://dx.doi.org/10.1186/s13148-016-0217-2