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Obesity-related DNA methylation at imprinted genes in human sperm: Results from the TIEGER study
BACKGROUND: Epigenetic reprogramming in mammalian gametes resets methylation marks that regulate monoallelic expression of imprinted genes. In males, this involves erasure of the maternal methylation marks and establishment of paternal-specific methylation to appropriately guide normal development....
Autores principales: | Soubry, Adelheid, Guo, Lisa, Huang, Zhiqing, Hoyo, Cathrine, Romanus, Stephanie, Price, Thomas, Murphy, Susan K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859994/ https://www.ncbi.nlm.nih.gov/pubmed/27158277 http://dx.doi.org/10.1186/s13148-016-0217-2 |
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