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Immunotherapy with methyl gallate, an inhibitor of Treg cell migration, enhances the anti-cancer effect of cisplatin therapy

Foxp3(+) CD25(+)CD4(+) regulatory T (Treg) cells are crucial for the maintenance of immunological self-tolerance and are abundant in tumors. Most of these cells are chemo-attracted to tumor tissues and suppress anti-tumor responses inside the tumor. Currently, several cancer immunotherapies targetin...

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Detalles Bibliográficos
Autores principales: Kim, Hyunseong, Lee, Gihyun, Sohn, Sung-Hwa, Lee, Chanju, Kwak, Jung Won, Bae, Hyunsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860368/
https://www.ncbi.nlm.nih.gov/pubmed/27162480
http://dx.doi.org/10.4196/kjpp.2016.20.3.261