NecroX-5 exerts anti-inflammatory and anti-fibrotic effects via modulation of the TNFα/Dcn/TGFβ1/Smad2 pathway in hypoxia/reoxygenation-treated rat hearts

Inflammatory and fibrotic responses are accelerated during the reperfusion period, and excessive fibrosis and inflammation contribute to cardiac malfunction. NecroX compounds have been shown to protect the liver and heart from ischemia-reperfusion injury. The aim of this study was to further define...

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Detalles Bibliográficos
Autores principales: Thu, Vu Thi, Kim, Hyoung Kyu, Long, Le Thanh, Thuy, To Thanh, Huy, Nguyen Quang, Kim, Soon Ha, Kim, Nari, Ko, Kyung Soo, Rhee, Byoung Doo, Han, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860373/
https://www.ncbi.nlm.nih.gov/pubmed/27162485
http://dx.doi.org/10.4196/kjpp.2016.20.3.305

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