Effects of hydrogen peroxide on voltage-dependent K(+) currents in human cardiac fibroblasts through protein kinase pathways

Human cardiac fibroblasts (HCFs) have various voltage-dependent K(+) channels (VDKCs) that can induce apoptosis. Hydrogen peroxide (H(2)O(2)) modulates VDKCs and induces oxidative stress, which is the main contributor to cardiac injury and cardiac remodeling. We investigated whether H(2)O(2) could m...

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Detalles Bibliográficos
Autores principales: Bae, Hyemi, Lee, Donghee, Kim, Young-Won, Choi, Jeongyoon, Lee, Hong Jun, Kim, Sang-Wook, Kim, Taeho, Noh, Yun-Hee, Ko, Jae-Hong, Bang, Hyoweon, Lim, Inja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860374/
https://www.ncbi.nlm.nih.gov/pubmed/27162486
http://dx.doi.org/10.4196/kjpp.2016.20.3.315

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