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Galectin-3 Binds to Lubricin and Reinforces the Lubricating Boundary Layer of Articular Cartilage
Lubricin is a mucinous, synovial fluid glycoprotein that enables near frictionless joint motion via adsorption to the surface of articular cartilage and its lubricating properties in solution. Extensive O-linked glycosylation within lubricin’s mucin-rich domain is critical for its boundary lubricati...
Autores principales: | Reesink, Heidi L., Bonnevie, Edward D., Liu, Sherry, Shurer, Carolyn R., Hollander, Michael J., Bonassar, Lawrence J., Nixon, Alan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860590/ https://www.ncbi.nlm.nih.gov/pubmed/27157803 http://dx.doi.org/10.1038/srep25463 |
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