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Force Generation by Membrane-Associated Myosin-I

Vertebrate myosin-IC (Myo1c) is a type-1 myosin that links cell membranes to the cytoskeleton via its actin-binding motor domain and its phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P(2))-binding tail domain. While it is known that Myo1c bound to PtdIns(4,5)P(2) in fluid-lipid bilayers can prop...

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Detalles Bibliográficos
Autores principales: Pyrpassopoulos, Serapion, Arpağ, Göker, Feeser, Elizabeth A., Shuman, Henry, Tüzel, Erkan, Ostap, E. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860596/
https://www.ncbi.nlm.nih.gov/pubmed/27156719
http://dx.doi.org/10.1038/srep25524