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Identification of cancer-driver genes in focal genomic alterations from whole genome sequencing data
DNA copy number alterations (CNAs) are the main genomic events that occur during the initiation and development of cancer. Distinguishing driver aberrant regions from passenger regions, which might contain candidate target genes for cancer therapies, is an important issue. Several methods for identi...
Autores principales: | Jang, Ho, Hur, Youngmi, Lee, Hyunju |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860638/ https://www.ncbi.nlm.nih.gov/pubmed/27156852 http://dx.doi.org/10.1038/srep25582 |
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