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p53-dependent SIRT6 expression protects Aβ42-induced DNA damage
Alzheimer’s disease (AD) is the most common type of dementia and age-related neurodegenerative disease. Elucidating the cellular changes that occur during ageing is an important step towards understanding the pathogenesis and progression of neurodegenerative disorders. SIRT6 is a member of the mamma...
Autores principales: | Jung, Eun Sun, Choi, Hyunjung, Song, Hyundong, Hwang, Yu Jin, Kim, Ahbin, Ryu, Hoon, Mook-Jung, Inhee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860716/ https://www.ncbi.nlm.nih.gov/pubmed/27156849 http://dx.doi.org/10.1038/srep25628 |
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