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A genome-wide IR-induced RAD51 foci RNAi screen identifies CDC73 involved in chromatin remodeling for DNA repair

To identify new regulators of homologous recombination repair, we carried out a genome-wide short-interfering RNA screen combined with ionizing irradiation using RAD51 foci formation as readout. All candidates were confirmed by independent short-interfering RNAs and validated in secondary assays lik...

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Detalles Bibliográficos
Autores principales:	Herr, Patrick, Lundin, Cecilia, Evers, Bastiaan, Ebner, Daniel, Bauerschmidt, Christina, Kingham, Guy, Palmai-Pallag, Timea, Mortusewicz, Oliver, Frings, Oliver, Sonnhammer, Erik, Helleday, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860774/ https://www.ncbi.nlm.nih.gov/pubmed/27462432 http://dx.doi.org/10.1038/celldisc.2015.34

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