Enhancement of the in vivo persistence and antitumor efficacy of CD19 chimeric antigen receptor T cells through the delivery of modified TERT mRNA

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Chimeric antigen receptor T cell immunotherapy is a promising therapeutic strategy for treating tumors, demonstrating its efficiency in eliminating several hematological malignancies in recent years. However, a major obstacle associated with current chimeric antigen receptor T cell immunotherapy is...

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Detalles Bibliográficos
Autores principales: Bai, Yun, Kan, Shifeng, Zhou, Shixin, Wang, Yuting, Xu, Jun, Cooke, John P, Wen, Jinhua, Deng, Hongkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860832/
https://www.ncbi.nlm.nih.gov/pubmed/27462436
http://dx.doi.org/10.1038/celldisc.2015.40
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