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Selected SNARE proteins are essential for the polarized membrane insertion of igf-1 receptor and the regulation of initial axonal outgrowth in neurons

The establishment of polarity necessitates initial axonal outgrowth and, therefore, the addition of new membrane to the axon’s plasmalemma. Axolemmal expansion occurs by exocytosis of plasmalemmal precursor vesicles (PPVs) primarily at the neuronal growth cone. Little is known about the SNAREs famil...

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Detalles Bibliográficos
Autores principales: Grassi, Diego, Plonka, Florentyna Bustos, Oksdath, Mariana, Guil, Alvaro Nieto, Sosa, Lucas J, Quiroga, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860833/
https://www.ncbi.nlm.nih.gov/pubmed/27462422
http://dx.doi.org/10.1038/celldisc.2015.23