Increased dysbindin-1B isoform expression in schizophrenia and its propensity in aggresome formation

Genetic variations in the human dysbindin-1 gene (DTNBP1) have been associated with schizophrenia. As a result of alternative splicing, the human DTNBP1 gene generates at least three distinct protein isoforms, dysbindin-1A, -1B and -1C. Significant effort has focused on dysbindin-1A, an important pl...

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Detalles Bibliográficos
Autores principales: Xu, Yiliang, Sun, Yuhui, Ye, Haihong, Zhu, Li, Liu, Jianghong, Wu, Xiaofeng, Wang, Le, He, Tingting, Shen, Yan, Wu, Jane Y, Xu, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860834/
https://www.ncbi.nlm.nih.gov/pubmed/27462430
http://dx.doi.org/10.1038/celldisc.2015.32

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