Structural basis for Sfm1 functioning as a protein arginine methyltransferase

SPOUT proteins constitute one class of methyltransferases, which so far are found to exert activity mainly towards RNAs. Previously, yeast Sfm1 was predicted to contain a SPOUT domain but can methylate ribosomal protein S3. Here we report the crystal structure of Sfm1, which comprises of a typical S...

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Detalles Bibliográficos
Autores principales: Lv, Fengjuan, Zhang, Tianlong, Zhou, Zhen, Gao, Shuaixin, Wong, Catherine CL, Zhou, Jin-Qiu, Ding, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860837/
https://www.ncbi.nlm.nih.gov/pubmed/27462434
http://dx.doi.org/10.1038/celldisc.2015.37

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