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Cell cycle-dependent inhibition of 53BP1 signaling by BRCA1

DNA damage response mediator protein 53BP1 is a key regulator of non-homologous end-joining (NHEJ) repair. 53BP1 protects DNA broken ends from resection by recruiting two downstream factors, RIF1 (RAP1-interacting factor 1) and PTIP (Pax transactivation domain-interacting protein), to double-strande...

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Detalles Bibliográficos
Autores principales:	Feng, Lin, Li, Nan, Li, Yujing, Wang, Jiadong, Gao, Min, Wang, Wenqi, Chen, Junjie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860855/ https://www.ncbi.nlm.nih.gov/pubmed/27462418 http://dx.doi.org/10.1038/celldisc.2015.19

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