Cargando…
SMG7 is a critical regulator of p53 stability and function in DNA damage stress response
The p53 tumor suppressor functions as a transcription factor and plays a pivotal role in regulation of cellular response to DNA damage by activating various genes including those involved in cell cycle arrest. p53 stability is essential for its function during stress response; however, the molecular...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860962/ https://www.ncbi.nlm.nih.gov/pubmed/27462439 http://dx.doi.org/10.1038/celldisc.2015.42 |