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Conserved regulators of Rag GTPases orchestrate amino acid-dependent TORC1 signaling
The highly conserved target of rapamycin complex 1 (TORC1) is the central component of a signaling network that couples a vast range of internal and external stimuli to cell growth, proliferation and metabolism. TORC1 deregulation is associated with a number of human pathologies, including many canc...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860963/ https://www.ncbi.nlm.nih.gov/pubmed/27462445 http://dx.doi.org/10.1038/celldisc.2015.49 |