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Conserved regulators of Rag GTPases orchestrate amino acid-dependent TORC1 signaling

The highly conserved target of rapamycin complex 1 (TORC1) is the central component of a signaling network that couples a vast range of internal and external stimuli to cell growth, proliferation and metabolism. TORC1 deregulation is associated with a number of human pathologies, including many canc...

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Detalles Bibliográficos
Autores principales: Powis, Katie, De Virgilio, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4860963/
https://www.ncbi.nlm.nih.gov/pubmed/27462445
http://dx.doi.org/10.1038/celldisc.2015.49