Cargando…

Integrative Pathway Analysis of Metabolic Signature in Bladder Cancer: A Linkage to The Cancer Genome Atlas Project and Prediction of Survival

PURPOSE: We used targeted mass spectrometry to study the metabolic fingerprint of urothelial cancer and determine whether the biochemical pathway analysis gene signature would have a predictive value in independent cohorts of patients with bladder cancer. MATERIALS AND METHODS: Pathologically evalua...

Descripción completa

Detalles Bibliográficos
Autores principales:	von Rundstedt, Friedrich-Carl, Rajapakshe, Kimal, Ma, Jing, Arnold, James M., Gohlke, Jie, Putluri, Vasanta, Krishnapuram, Rashmi, Piyarathna, D. Badrajee, Lotan, Yair, Gödde, Daniel, Roth, Stephan, Störkel, Stephan, Levitt, Jonathan M., Michailidis, George, Sreekumar, Arun, Lerner, Seth P., Coarfa, Cristian, Putluri, Nagireddy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2016
Materias:	Investigative Urology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861129/ https://www.ncbi.nlm.nih.gov/pubmed/26802582 http://dx.doi.org/10.1016/j.juro.2016.01.039

Ejemplares similares

Expression of ganglioside GD2, reprogram the lipid metabolism and EMT phenotype in bladder cancer
por: Vantaku, Venkatrao, et al.
Publicado: (2017)

Correction: Expression of ganglioside GD2, reprogram the lipid metabolism and EMT phenotype in bladder cancer
por: Vantaku, Venkatrao, et al.
Publicado: (2019)

Lipid Alterations in African American Men with Prostate Cancer
por: Ravindran, Anindita, et al.
Publicado: (2021)

Lipidomic Profiling Identifies a Novel Lipid Signature Associated with Ethnicity-Specific Disparity of Bladder Cancer
por: Kami Reddy, Karthik Reddy, et al.
Publicado: (2022)

EMT-induced metabolite signature identifies poor clinical outcome
por: Bhowmik, Salil Kumar, et al.
Publicado: (2015)

Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells
por: Shafi, Ayesha A., et al.
Publicado: (2015)

Unbiased Lipidomic Profiling of Triple-Negative Breast Cancer Tissues Reveals the Association of Sphingomyelin Levels with Patient Disease-Free Survival
por: Purwaha, Preeti, et al.
Publicado: (2018)

Methionine-Homocysteine Pathway in African-American Prostate Cancer
por: Gohlke, Jie H, et al.
Publicado: (2019)

Cisplatin generates oxidative stress which is accompanied by rapid shifts in central carbon metabolism
por: Yu, Wangie, et al.
Publicado: (2018)

Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer
por: Bader, David A., et al.
Publicado: (2018)

Metabolomic Profiling Reveals a Role for Androgen in Activating Amino Acid Metabolism and Methylation in Prostate Cancer Cells
por: Putluri, Nagireddy, et al.
Publicado: (2011)

Conjugated bile acids are nutritionally re-programmable antihypertensive metabolites
por: Chakraborty, Saroj, et al.
Publicado: (2023)

Current Applications of Metabolomics in Cirrhosis
por: Khan, Vinshi, et al.
Publicado: (2018)

Steroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer Cells
por: Szwarc, Maria M., et al.
Publicado: (2018)

Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative DNA Damage in Human Pulmonary Cells
por: Burke, Rebecca, et al.
Publicado: (2021)

Analysis of cerebrospinal fluid metabolites in patients with primary or metastatic central nervous system tumors
por: Ballester, Leomar Y., et al.
Publicado: (2018)

Uridine Diphosphate Glucuronosyl Transferase 2B28 (UGT2B28) Promotes Tumor Progression and Is Elevated in African American Prostate Cancer Patients
por: Ravindran, Anindita, et al.
Publicado: (2022)

Plasma Urea Cycle Metabolites May Be Useful Biomarkers in Children With Eosinophilic Esophagitis
por: Moye, Lindsay M., et al.
Publicado: (2019)

Integrative metabolomics and transcriptomics analysis reveals novel therapeutic vulnerabilities in lung cancer
por: Thaiparambil, Jose, et al.
Publicado: (2022)

Pathway-Centric Integrative Analysis Identifies RRM2 as a Prognostic Marker in Breast Cancer Associated with Poor Survival and Tamoxifen Resistance()()()
por: Putluri, Nagireddy, et al.
Publicado: (2014)

Acquisition of Cisplatin Resistance Shifts Head and Neck Squamous Cell Carcinoma Metabolism toward Neutralization of Oxidative Stress
por: Yu, Wangjie, et al.
Publicado: (2020)

Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer
por: Dasgupta, Subhamoy, et al.
Publicado: (2018)

Influence of lymph node degeneration on metastases in prostate cancer: or why we must look for a needle in a haystack
por: Gödde, Daniel, et al.
Publicado: (2023)

Influence of the neural microenvironment on prostate cancer
por: Coarfa, Christian, et al.
Publicado: (2017)

Calcium/calmodulin-dependent protein kinase kinase 2 regulates hepatic fuel metabolism
por: Stork, Brittany A., et al.
Publicado: (2022)

IDO1 Expression in Ovarian Cancer Induces PD-1 in T Cells via Aryl Hydrocarbon Receptor Activation
por: Amobi-McCloud, Adaobi, et al.
Publicado: (2021)

Potential role of Plasmodium falciparum exported protein 1 in the chloroquine mode of action
por: Lisewski, Andreas Martin, et al.
Publicado: (2017)

Glutathione peroxidase 2 is a metabolic driver of the tumor immune microenvironment and immune checkpoint inhibitor response
por: Ahmed, Kazi Mokim, et al.
Publicado: (2022)

Systematic analysis of human telomeric dysfunction using inducible telosome/shelterin CRISPR/Cas9 knockout cells
por: Kim, Hyeung, et al.
Publicado: (2017)

The Diagnostic Performance of Cxbladder Resolve, Alone and in Combination with Other Cxbladder Tests, in the Identification and Priority Evaluation of Patients at Risk for Urothelial Carcinoma
por: Raman, Jay D., et al.
Publicado: (2021)

Degenerative Changes in Aging Human Pelvic Lymph Nodes—A Reason to Rethink Staging and Therapy of Regional Malignancies?
por: Gödde, Daniel, et al.
Publicado: (2023)

Cigarette smoke condensate induces centrosome clustering in normal lung epithelial cells
por: Thaiparambil, Jose, et al.
Publicado: (2023)

Thioredoxin Reductase is a major regulator of metabolism in leukemia cells
por: Karunanithi, Sheelarani, et al.
Publicado: (2021)

Pentose Phosphate Shunt Modulates Reactive Oxygen Species and Nitric Oxide Production Controlling Trypanosoma cruzi in Macrophages
por: Koo, Sue-jie, et al.
Publicado: (2018)

Epigenome environment interactions accelerate epigenomic aging and unlock metabolically restricted epigenetic reprogramming in adulthood
por: Treviño, Lindsey S., et al.
Publicado: (2020)

Platelet-Synthesized Testosterone in Men with Prostate Cancer Induces Androgen Receptor Signaling()
por: Zaslavsky, Alexander B., et al.
Publicado: (2015)

High throughput microscopy identifies bisphenol AP, a bisphenol A analog, as a novel AR down-regulator
por: Stossi, Fabio, et al.
Publicado: (2016)

CAPER Is Vital for Energy and Redox Homeostasis by Integrating Glucose-Induced Mitochondrial Functions via ERR-α-Gabpa and Stress-Induced Adaptive Responses via NF-κB-cMYC
por: Kang, Yun Kyoung, et al.
Publicado: (2015)

A Needle in the Haystack: A Rare Case of Spontaneous Tumor Lysis in Newly Diagnosed Chronic Lymphocytic Leukemia Unmasked by Acute Renal Failure
por: Desai, Milap, et al.
Publicado: (2020)

2d Di-Hadron Correlations at $\sqrt(s_NN)$ = 2.76 TeV using the ALICE Experiment
por: Piyarathna, Badrajee
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_spnc2vsutjno7b6u9r17s728m5