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The Effects of Chemotherapeutic Agents, Bleomycin, Etoposide, and Cisplatin, on Chromatin Remodeling in Male Rat Germ Cells

The coadministration of bleomycin, etoposide, and cisplatin (BEP) has increased the survival rate of testicular cancer patients to over 90%. Previous studies have demonstrated that BEP induces germ cell damage during the final stages of spermatogenesis, when major chromatin remodeling occurs. Chroma...

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Detalles Bibliográficos
Autores principales: Bagheri-Sereshki, Negar, Hales, Barbara F., Robaire, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for the Study of Reproduction, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861167/
https://www.ncbi.nlm.nih.gov/pubmed/26911428
http://dx.doi.org/10.1095/biolreprod.115.137802

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