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Vaccine development for allergen-specific immunotherapy based on recombinant allergens and synthetic allergen peptides: Lessons from the past and novel mechanisms of action for the future

In the past, the development of more effective, safe, convenient, broadly applicable, and easy to manufacture vaccines for allergen-specific immunotherapy (AIT) has been limited by the poor quality of natural allergen extracts. Progress made in the field of molecular allergen characterization has no...

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Detalles Bibliográficos
Autores principales: Valenta, Rudolf, Campana, Raffaela, Focke-Tejkl, Margit, Niederberger, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861208/
https://www.ncbi.nlm.nih.gov/pubmed/26853127
http://dx.doi.org/10.1016/j.jaci.2015.12.1299