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Optimization of Liver Decellularization Maintains Extracellular Matrix Micro-Architecture and Composition Predisposing to Effective Cell Seeding
Hepatic tissue engineering using decellularized scaffolds is a potential therapeutic alternative to conventional transplantation. However, scaffolds are usually obtained using decellularization protocols that destroy the extracellular matrix (ECM) and hamper clinical translation. We aim to develop a...
Autores principales: | Maghsoudlou, Panagiotis, Georgiades, Fanourios, Smith, Holly, Milan, Anna, Shangaris, Panicos, Urbani, Luca, Loukogeorgakis, Stavros P., Lombardi, Benedetta, Mazza, Giuseppe, Hagen, Charlotte, Sebire, Neil J., Turmaine, Mark, Eaton, Simon, Olivo, Alessandro, Godovac-Zimmermann, Jasminka, Pinzani, Massimo, Gissen, Paul, De Coppi, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861300/ https://www.ncbi.nlm.nih.gov/pubmed/27159223 http://dx.doi.org/10.1371/journal.pone.0155324 |
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