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Identifying Prognostic SNPs in Clinical Cohorts: Complementing Univariate Analyses by Resampling and Multivariable Modeling

Clinical cohorts with time-to-event endpoints are increasingly characterized by measurements of a number of single nucleotide polymorphisms that is by a magnitude larger than the number of measurements typically considered at the gene level. At the same time, the size of clinical cohorts often is st...

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Detalles Bibliográficos
Autores principales: Hieke, Stefanie, Benner, Axel, Schlenk, Richard F., Schumacher, Martin, Bullinger, Lars, Binder, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861340/
https://www.ncbi.nlm.nih.gov/pubmed/27159447
http://dx.doi.org/10.1371/journal.pone.0155226