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Identifying Prognostic SNPs in Clinical Cohorts: Complementing Univariate Analyses by Resampling and Multivariable Modeling
Clinical cohorts with time-to-event endpoints are increasingly characterized by measurements of a number of single nucleotide polymorphisms that is by a magnitude larger than the number of measurements typically considered at the gene level. At the same time, the size of clinical cohorts often is st...
Autores principales: | Hieke, Stefanie, Benner, Axel, Schlenk, Richard F., Schumacher, Martin, Bullinger, Lars, Binder, Harald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861340/ https://www.ncbi.nlm.nih.gov/pubmed/27159447 http://dx.doi.org/10.1371/journal.pone.0155226 |
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