Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)

Ebola virus infection can cause severe hemorrhagic fever with a high mortality in humans. The outbreaks of Ebola viruses in 2014 represented the most serious Ebola epidemics in history and greatly threatened public health worldwide. The development of additional effective anti-Ebola therapeutic agen...

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Autores principales:	Zhou, Nan, Pan, Ting, Zhang, Junsong, Li, Qianwen, Zhang, Xue, Bai, Chuan, Huang, Feng, Peng, Tao, Zhang, Jianhua, Liu, Chao, Tao, Liang, Zhang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2016
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861487/ https://www.ncbi.nlm.nih.gov/pubmed/26953343 http://dx.doi.org/10.1074/jbc.M116.716100