Superoxide Dismutase (SOD)-mimetic M40403 Is Protective in Cell and Fly Models of Paraquat Toxicity: IMPLICATIONS FOR PARKINSON DISEASE

Parkinson disease is a debilitating and incurable neurodegenerative disorder affecting ∼1–2% of people over 65 years of age. Oxidative damage is considered to play a central role in the progression of Parkinson disease and strong evidence links chronic exposure to the pesticide paraquat with the inc...

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Detalles Bibliográficos
Autores principales: Filograna, Roberta, Godena, Vinay K., Sanchez-Martinez, Alvaro, Ferrari, Emanuele, Casella, Luigi, Beltramini, Mariano, Bubacco, Luigi, Whitworth, Alexander J., Bisaglia, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Molecular Bases of Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861490/
https://www.ncbi.nlm.nih.gov/pubmed/26953346
http://dx.doi.org/10.1074/jbc.M115.708057

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