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Structural characterization of ribosome recruitment and translocation by type IV IRES
Viral mRNA sequences with a type IV IRES are able to initiate translation without any host initiation factors. Initial recruitment of the small ribosomal subunit as well as two translocation steps before the first peptidyl transfer are essential for the initiation of translation by these mRNAs. Usin...
Autores principales: | Murray, Jason, Savva, Christos G, Shin, Byung-Sik, Dever, Thomas E, Ramakrishnan, V, Fernández, Israel S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861600/ https://www.ncbi.nlm.nih.gov/pubmed/27159451 http://dx.doi.org/10.7554/eLife.13567 |
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