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Structural characterization of ribosome recruitment and translocation by type IV IRES

Viral mRNA sequences with a type IV IRES are able to initiate translation without any host initiation factors. Initial recruitment of the small ribosomal subunit as well as two translocation steps before the first peptidyl transfer are essential for the initiation of translation by these mRNAs. Usin...

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Detalles Bibliográficos
Autores principales: Murray, Jason, Savva, Christos G, Shin, Byung-Sik, Dever, Thomas E, Ramakrishnan, V, Fernández, Israel S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861600/
https://www.ncbi.nlm.nih.gov/pubmed/27159451
http://dx.doi.org/10.7554/eLife.13567

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