Coupling of HIV-1 Antigen to the Selective Autophagy Receptor SQSTM1/p62 Promotes T-Cell-Mediated Immunity

Vaccines aiming to promote T-cell-mediated immune responses have so far showed limited efficacy, and there is a need for novel strategies. Studies indicate that autophagy plays an inherent role in antigen processing and presentation for CD4(+) and CD8(+) T cells. Here, we report a novel vaccine stra...

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Detalles Bibliográficos
Autores principales: Andersen, Aram Nikolai, Landsverk, Ole Jørgen, Simonsen, Anne, Bogen, Bjarne, Corthay, Alexandre, Øynebråten, Inger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861724/
https://www.ncbi.nlm.nih.gov/pubmed/27242780
http://dx.doi.org/10.3389/fimmu.2016.00167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861724/
https://www.ncbi.nlm.nih.gov/pubmed/27242780
http://dx.doi.org/10.3389/fimmu.2016.00167

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