Cargando…
Coupling of HIV-1 Antigen to the Selective Autophagy Receptor SQSTM1/p62 Promotes T-Cell-Mediated Immunity
Vaccines aiming to promote T-cell-mediated immune responses have so far showed limited efficacy, and there is a need for novel strategies. Studies indicate that autophagy plays an inherent role in antigen processing and presentation for CD4(+) and CD8(+) T cells. Here, we report a novel vaccine stra...
Autores principales: | Andersen, Aram Nikolai, Landsverk, Ole Jørgen, Simonsen, Anne, Bogen, Bjarne, Corthay, Alexandre, Øynebråten, Inger |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861724/ https://www.ncbi.nlm.nih.gov/pubmed/27242780 http://dx.doi.org/10.3389/fimmu.2016.00167 |
Ejemplares similares
-
ZZ-dependent regulation of p62/SQSTM1 in autophagy
por: Zhang, Yi, et al.
Publicado: (2018) -
p62/SQSTM1 synergizes with autophagy for tumor growth in vivo
por: Wei, Huijun, et al.
Publicado: (2014) -
Involvement of autophagy in MHC class I antigen presentation
por: Øynebråten, Inger
Publicado: (2020) -
Autophagy mediates epithelial cancer chemoresistance by reducing p62/SQSTM1 accumulation
por: Battista, R. Alessia, et al.
Publicado: (2018) -
SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair
por: Hewitt, Graeme, et al.
Publicado: (2016)