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Small-Molecule Binding Aptamers: Selection Strategies, Characterization, and Applications
Aptamers are single-stranded, synthetic oligonucleotides that fold into 3-dimensional shapes capable of binding non-covalently with high affinity and specificity to a target molecule. They are generated via an in vitro process known as the Systematic Evolution of Ligands by EXponential enrichment, f...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4861895/ https://www.ncbi.nlm.nih.gov/pubmed/27242994 http://dx.doi.org/10.3389/fchem.2016.00014 |